Randall Davis, MD

Professor of Medicine, Microbiology, and Biochemistry and Molecular Genetics and Director of the UAB Multidisciplinary Molecular Interaction (MMIC) Core Facility

Dr. Davis' laboratory is focused on the cellular and molecular immunobiology of lymphocytes in normal and diseased conditions. He has been broadly trained as a physician-scientist with a background in basic lymphocyte development and receptor biology. As a postdoctoral fellow he co-discovered a multigene family that encodes Fc receptor-like (FCRL) molecules with tyrosine-based regulatory potential that are expressed by subpopulations of lymphocytes in normal and diseased states. Current work involves investigating FCRL members in humans and mice to define their functional roles in normal and aberrant immune conditions. Work by his group and through productive collaborations has provided a better understanding of these receptors in basic immunology as well as in clinically important autoimmune and malignant conditions. Beyond his role as a physician-scientist, he also serves as Director of the UAB Multidisciplinary Molecular Interaction (MMIC) Core Facility which supports the operation of a Biacore T200 instrument. This technology allows for the determination of very sensitive kinetic interactions between macromolecules and/or small drugs using surface plasmon resonance (SPR).

http://www.ncbi.nlm.nih.gov/pubmed/?term=Davis%20RS

UAB Department of Medicine Walter B. Frommeyer, Jr., Fellowship in Investigative Medicine Physician Scientist Award (2000-2001); UAB Department of Medicine J. Claude Bennett Award for Excellence in Research by an Associate Fellow (2001, 2002); Leukemia and Lymphoma Society Special Fellow Career Development Award (2003); NIH-NIAID K08 Mentored Clinical Scientist Development Award (2003); Dana Foundation Human Immunology Program Award (2005); V Foundation for Cancer Research Scholar Award (2005); Member, Henry Kunkel Society (2006); Cancer Research Institute Investigator Award (2006); American Cancer Society Research Scholar Award (2008); CLL Global Research Foundation Award (2008); Member, Southern Society for Clinical Investigation (2012); Lupus Research Institute Novel Research Grant Award (2013); Leukemia Lymphoma Society Translation Research Award (2016).

American Association of Immunologists (AAI)
American Society of Hematology (ASH)
Henry Kunkel Society
Southern Society for Clinical Investigation (SSCI)

https://scholars.uab.edu/513-Randall-Davis