Andrzej Slominski, MD, PhD

Biography

Title

Tenured Professor of Dermatology, Professor of Pathology

Faculty Appointment

Professor

Research Interests

As a physician-scientist trained by Aaron Lerner and John Pawelek in pigment biology and melanoma and by Martin Mihm in skin pathology, I have a longstanding (>30 years) and unbroken trajectory of research (skin, cellular and molecular biology, biochemistry, melanin pigmentation, cancer, photobiology and endocrinology) and clinical (dermatopathology and pathology) activities with >370 peer reviewed papers. My recent focus is on neuroendocrinology of the skin, cancer, photobiology, pigment biology, cutaneous steroidogenesis, vitamin D plus novel secosteroids and melatonin. My contribution to the International and Pan-American Pigment Cell and Melanoma communities is exemplified by service as secretary/treasurer or council member of the PASPCR, secretary of the IFPCS and past membership in the Steering Committee of the MSR. My academic track record is marked by discoveries of cutaneous expression of classical hypothalamic and pituitary hormones, discoveries of cutaneous serotoninergic and melatoninergic systems, and defining the skin as a neuroendocrine organ. Most important is the discovery of new seco/steroidogenic pathways. I am also board certified in pathology and have strong expertise in animal models of cancer

Awards & Recognition

Last Ten years
2019 Invited Speaker: “"Novel Pathways of Vitamin D and Lumisterol Activation and Their Role in the Epidermis Functions" during Gordon Research Conference on the Barrier Function of Mammalian Skin, August 11-16, 2019, Waterville Valley, NH, USA
2019 Chair of two sessions: I. Historic and Future Perspective of Vitamin D3, and II. Molecular Biology of Vitamin D – New Insights in Vitamin D Receptor Function/Structure and Beyond. during Joint International Symposium on Vitamin D in Prevention and Therapy & Biologic Effects of Light. June 5-7, 2019, Schlossberg, Homburg, Germany
2018-2021 Chair of the Continuing Education and Research Committee, American Society of Dermatopathology
2018 Full Member of the World Academy of Sciences
2017 Co-chair of the concurrent Session UV Response and DNA Repair Melanoma of the International Pigment Cell Conference, Denver, CO, August 27-30, 2017
2017 Invited visiting Professor and Lecturer at the Jagiellonian University, Krakow, May 8-22, 2017
2017 Invited Lecturer at the Medical University of Gdansk, May 2017, Gdansk, Poland
2015-2018 Member of Continuing Education and Research Committee, and the vice-Chair, American Society of Dermatopathology
2016-2018 Elected Council Member of the Panamerican Society for Pigment Cell Research
2015 Speaker for the GRC on Barrier Function of Mammalian Skin, August 16-21, 2015 at Waterville Valley, NH: “Cutaneous melatoninergic and secosteroidogenic systems as protectors of epidermal integrity.”
2015 Distinguished Scientist Leadership Society Speaker Series, Amway, Grand Rapids, May 28, 2015: “Ultraviolet, vitamin D, melanin and the skin: What’s new under the sun?
2014-2015 Elected Council Member of the Panamerican Society for Pigment Cell Research
2014 Member of Scientific Advisory Board for XXII International Pigment Cell Conference (IPCC 2014), September 2014, Singapore
2013 Member of the scientific committee for the 18th PASPCR Annual Meeting in Madison, WI, September, 2013
2013 Co-chair of the Satellite Symposium Dermatoendocrinology, May 7, 2013, to the IID tricontinental meeting, Edinburgh, Scotland, May 7-11.
2012 Member of the scientific committee for the 17th PASPCR Annual Meeting in Salt Lake City, Utah, September /October , 2012
2011-2014 Elected Secretary of the International Federation of Pigment Cell Societies
2011 Co- chair of the joint Society for Melanoma Research/Pan-American Society for Pigment Cell Research session on 11/10 during the 8th International Congress of The Society for Melanoma Research, 11/ 9-11/2011, Tampa, FL
2011 Co-chair of the Session “Neuroendocrinology of pigmentation and MC1R” During XXI International Pigment Cell Conference (IPCC). ‘‘Skin and Other Pigment Cells: Bridging Clinical Medicine and Science’’. 9/20-24, 2011, Bordeaux, France.
2011 Member of Scientific Advisory Board for International Society for Pigment Cell Research Meeting in Bordeaux, France 9/ 2011
2010 Member of Scientific Advisory Board for 16th PASPCR Meeting in Vancouver, Canada; 9/10, 2010
2009 Chairman of the Session “Pigment cell Biology of the Hair Follicle” during 15th meeeitng of the European Society for Pigment Cell Research, Munster, Germany, September 21-23, 2009
2009 Chairman of the 15th Annual Meeting of the Panamerican Pigment Cell Society, “ The Pigmentary System: Securing a Place Under the Sun”, September 4-7, 2009, Memphis, TN, USA
2009 Invited Speaker : "Neuroendocrine functions of the skin" of the 2009 US Technical Symposium of The International Society for Bioengineering and Skin Imaging (ISBS), March 19, 2009, Dallas, TX.
2009 Invited Speaker: “Neuroendocrinology of the pigmentary system”, February 25, 2009. Dowling Club Lectures, University of California, Irvine
Current Funding
2019-2023 VA Merit 1 I01 BX004293-01A1, Department of Veterans Affairs (Slominski, PI) 3 cal. months “CYP11A1-derived secosteroids as therapeutic agents in UVB induced skin cancer”
2018-2023 1R01AR073004 - 01A1 NIH/NIAMS (Slominski A, PI) 3.00 cal. months "Mechanism of action and function of novel secosteroid 20(OH)D3 in the skin"
2017-2022 1 RO1 AR071189-01A1 NIH/NIAMS (Slominski, PI) 3.00 cal. months “Significance of metabolic activation of lumisterol in the skin.”
2017-2022 PAR-15-023 NIH/NCI (Elmets, PI) Co-I with 0.7 cal. months
“RXR Rexinoids for cancer chemoprevention”
2016-2021 1R01ES026219-01A (NIEHS), (Athar, PI); Co-I with 0.6 calendar months “Chemoprevention of environmental UVB-induced skin cancer in immunosuppressed mice
2016-2020 1I01BX003395-01 VA Merit Department of VA, (Elmets, PI); Co-I with 1.2 calendar months “Host Defense Mechanisms in Melanoma Pathogenesis”
2015-2018 National Science Centre, Poland (2014/15/B/NZ4/00751) (Brozyna, PI), Co-I “On the role of melanogenesis in regulation of melanoma behavior: clinical implication in stage 3/4”

Memberships

American Association for Cancer Research
American Society of Dermatopathology
American Physiological Society
College of American Pathologists
Endocrine Society
International Pigment Cell Society
International Society of Dermatopathology
Panamerican Society for Pigment Cell Research
Society for Investigative Dermatology

View Academic Profile

https://scholars.uab.edu/2981-Andrzej-Slominski